SMS scnews item created by Catherine Meister at Fri 20 Mar 2026 1235
Type: Seminar
Distribution: World
Expiry: 3 Apr 2026
Calendar1: 26 Mar 2026 1300-1400
CalLoc1: SMRI Seminar Room (A12 Macleay Room 301)
CalTitle1: Immune Dysregulation in COVID-19: What Can Mathematical Modeling Tell Us?
Auth: cmeister@159-196-153-133.9fc499.syd.nbn.aussiebb.net (cmei0631) in SMS-SAML

SMRI Seminar

Immune Dysregulation in COVID-19: What Can Mathematical Modeling Tell Us?

Ryu

Hwayeon Ryu, Elon University

SMRI Seminar, Thursday 26th March 2026, 1 pm – 2 pm, SMRI Seminar Room (A12 Macleay Room 301)

Abstract: Why do some people experience mild COVID-19 while others develop severe disease? A key part of the answer lies in how the immune system responds to viral infection. In this talk, I present a mathematical model of the interaction between SARS-CoV-2 and the immune system, focusing on the role of key immune components. While a well coordinated immune response helps control the virus, its dysregulation can drive severe disease. Using simulations and sensitivity analysis, we explore how different immune responses lead to divergent outcomes and identify key mechanisms that shape disease progression. We also use the model to examine how potential interventions might alter these dynamics. This work highlights how mathematical modeling can provide insight into complex immune processes and inform our understanding of disease severity and potential treatment strategies.

For seminar updates, see our What's On Calendar. Please join us after the seminar for the SMRI afternoon tea, every Thursday at 2 pm on the SMRI Terrace.

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