Dear All, We are delighted to present the MaPSS Seminar topic of Monday 11/09; please see the abstract below. **This Semester the Seminar will always run on Monday, at 5:00pm in 535A** Following the talk, there will be pizza on offer. Speaker: Bernard Ikhimwin (Sydney University) Title: Computational model of an initial lymphatic network Abstract: The lymphatic vascular system consists of networks of vessels which play a key role in immune surveillance by transporting lymph and protein from the tissue space back to the circulatory system. In contrast to the cardiovascular system which has a central pump, the lymphatic vascular system has no central pump, hence the transport of fluid against gravity relies on local extrinsic and intrinsic pumping. The initial lymphatics lack smooth muscle cells, hence they cannot perform intrinsic pumping, instead lymph is moved by means of extrinsic pumping, taking advantage of the relative motion of adjacent tissues. We used a lumped-parameter model to describe the transport of lymph through an initial lymphatic network of the mesentery by extrinsic pumping. In this talk we shall look at three different scenarios which are (a) Impermeable initial lymphatic network, (b) permeable initial lymphatic network and (c) tapering-permeable initial lymphatic network. I will discuss the implication of these results. Supervisors, please encourage your students to attend. Thanks, MaPSS Organizers