This Wednesday 14 May we will welcome Owen Dillon (School of Medical Imaging) who will be giving a seminar at 11am in **Carslaw 452** (note changed room). Afterwards we will go to lunch (free for students). Title: Cone Beam CT in lung cancer radiation therapy and Quantum CT for lung cancer screening Abstract: Cone Beam CT is a classic example of a linear(ized) inverse problem that has become widely used, particularly in guiding radiation therapy. A particular challenge in lung cancer radiation therapy is dealing with patient respiratory motion, which has motivated the development of 4D CBCT. By incorporating hardware control and reasonable patient models adaptive 4DCBCT was developed and tested in the ADAPT clinical trial to achieve 4DCBCT with 85% less imaging dose and 65% less imaging time. These results motivated additional hardware developments that now form the basis of a novel Quantum CT modality that can be used for 3D imaging during treatment delivery and is also well suited to rural lung cancer screening, albeit with additional constraints and approaches required to best solve the associated inverse problem.